His debut is marked by the encounter with Giovanni Testori and participation to the show Artisti e Scrittori at Rotonda della Besana, Milan. In 2004 Electa published Velasco 20, a monograph on his first twenty-years of activity, with a contribution of Giulio Giorello. Extramoenia (2004-2005) is an exhibition set up by the Sicily Region in Palermo (Palazzo Belmonte Riso) and Milan (Palazzo della Ragione). In 2005 Vitali was included in the collection of MACRO. Under the supervision of Danilo Eccher, he created Immagini, forme e natura delle Alpi (2007) and LATO4 (2008). Sbarco (2010) was set up at piazza Duomo and in the St. Augustine complex in Pietrasanta, as well as at piazza Duca d’Aosta and Palazzo Reale in Milan, under the supervision of Fernando Mazzocca and Francesco Poli.
In 2011 he was invited to the Italian Hall of the Venice Biennial Exhibition, where he exhibited the sculpture Veidrodis. The same year saw the release of Apriti Cielo, a book published by Skira, which contains a collection of watercolour paintings on the sacred theme: these include some of the drawings produced for the culture page of “Il Corriere della Sera”, to which Vitali has been a contributor since 2007. In 2012 the exhibition Foresta Rossa, curated by Luca Molinari, takes part on Isola Madre (Stresa) and Verbania, on Maggiore Lake.